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As the world's leading independent organization for children in need, Save the Children has programs in nearly 120 countries, including the United States. Their aim is to inspire breakthroughs in the way the world treats children, and to create immediate and lasting change in their lives by improving their health, education and economic opportunities. In times of acute crisis, Save the Children mobilizes rapid assistance to help children recover from the effects of war, conflict and natural disasters.

CARE is a leading humanitarian organization fighting global poverty. We place special focus on working alongside poor women because, equipped with the proper resources, women have the power to help whole families and entire communities escape poverty. Women are at the heart of CARE's community-based efforts to improve basic education, prevent the spread of HIV, increase access to clean water and sanitation, expand economic opportunity and protect natural resources. CARE also delivers emergency aid to survivors of war and natural disasters, and helps people rebuild their lives.

The mission of Doctors Without Borders/Médecins Sans Frontières (MSF) is to provide impartial medical relief to the victims of war, disease, and natural or man-made disaster, without regard to race, religion, or political affiliation. A non-profit, self-governed, member-based organisation, MSF's global reach is demonstrated by a presence in over 72 countries and territories with medical humanitarian projects, 9,904,200 medical consultations conducted by humanitarian teams, and 877,300 patients admitted to MSF hospitals or clinics around the world.

The National Multiple Sclerosis Society's mission is to cure multiple sclerosis while empowering people affected by multiple sclerosis (MS) to live their best lives. The organization pledges to accelerate cures through global leadership, and improve access to personalized, affordable, high-quality MS healthcare. It empowers people affected by MS to solve everyday challenges and strengthens the MS movement through more and deeper connections.

The Nature Conservancy is a global environmental nonprofit working to create a world where people and nature can thrive. Its mission is to conserve the lands and waters on which all life depends, by boldly addressing the biodiversity and climate crisis over the next decade, and maximizing the organization's ability to effect change between now and 2030, to shape a brighter future for people and our planet.

The Leukemia & Lymphoma Society® (LLS) is the global leader and innovator in creating a world without blood cancer. The LLS mission: Cure blood cancer and improve the quality of life of all patients and their families.

DignityMoves works to end unsheltered homelessness in communities by building Interim Supportive Housing as a rapid, cost-effective, and, thus, scalable solution.

Our mission is to channel the healing powers of the ocean to restore hope, renew purpose, and revitalize community. Operation Surf’s curriculum-based programs aim to inspire injured military and veterans to seek wellness in all aspects of their lives while providing the necessary resources, tools, and peer-to-peer support to continue this mindset indefinitely. By staying true to our core values of care, inclusion, commitment, integrity, and communication; we change participants’ lives – one wave at a time.

Oceana, the world's largest international organization focused exclusively on ocean conservation, was founded in 2001 by a group of leading foundations concerned that although the oceans constitute over 70 percent of the earth's surface, an extremely small percentage of environmental funding was dedicated to protecting them.  Oceana's campaigns are designed to change that by forcing clear, identifiable policy changes with real "in the water" results, usually in three to five years. Our international campaigns in North America, Europe, Chile, and Belize are focused on the actions agreed on by scientists throughout the world as necessary to preserve and restore marine life: Protect seafloor habitat from destructive bottom trawling; Set and enforce reasonable catch limits for commercial fishing; Stop subsidizing overcapacity in commercial fishing fleets; Stop marine pollution, particularly carbon dioxide emissions that are making the oceans more acidic; Oceana sets annual goals toward achieving specific changes and holds itself strictly accountable to its Board, funders, and supporters.  Since inception, Oceana has achieved dramatic success in protecting the world's oceans in targeted, practical ways.

Established in 1985, The ALS Association is dedicated to leading the fight to treat and cure ALS through global research and nationwide advocacy while also empowering people with Lou Gehrig's Disease and their families to live fuller lives by providing them with compassionate care and support. The Association builds hope and enhances the quality of life while aggressively searching for new treatments and a cure, through global research, providing assistance for people with ALS through a nationwide network of chapters, coordinating multidisciplinary care through certified clinical care centers, and fostering government partnerships.

The Salvation Army, an international movement, is an evangelical part of the universal Christian Church. Its message is based on the Bible. Its ministry is motivated by the love of God. Its mission is to preach the gospel of Jesus Christ and to meet human needs in His name without discrimination.

GlobalGiving makes it possible for anyone to give to community-led nonprofits all over the world. Our mission is to transform aid and philanthropy to accelerate community-led change. We make it possible for you to support local projects in 170 countries, giving nonprofits access to the funding, tools, and training they need to become more effective and to make our world a better place.