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St. Jude Children's Research Hospital seeks to advance cures, and means of prevention, for pediatric catastrophic diseases through research and treatment. Consistent with the vision of their founder Danny Thomas, no child is denied treatment based on race, religion or a family's ability to pay. St. Jude’s strives to be the world leader in advancing the treatment and prevention of catastrophic diseases in children, by providing outstanding patient care; conducting basic, translational and clinical research designed to elucidate biological mechanisms, understand disease pathogenesis, improve diagnosis, enhance treatment outcome, prevent diseases and minimize adverse consequences of treatment; and by educating health care and scientific research professionals. Treatments invented at St. Jude have helped push the overall childhood cancer survival rate from 20% to more than 80% since it opened more than 50 years ago.

Willie Nelson, Neil Young and John Mellencamp organized the first Farm Aid concert in 1985 to raise awareness about the loss of family farms and to raise funds to keep farm families on the land. Dave Matthews joined the Farm Aid Board of Directors in 2001, and Margo Price joined in 2021. Farm Aid has raised more than $85 million to promote a strong and resilient family farm system of agriculture. Farm Aid is a nonprofit organization whose mission is to build a vibrant, family farm-centered system of agriculture in America.

Our mission is to channel the healing powers of the ocean to restore hope, renew purpose, and revitalize community. Operation Surf’s curriculum-based programs aim to inspire injured military and veterans to seek wellness in all aspects of their lives while providing the necessary resources, tools, and peer-to-peer support to continue this mindset indefinitely. By staying true to our core values of care, inclusion, commitment, integrity, and communication; we change participants’ lives – one wave at a time.

Our vision is to foster an inclusive world for children with disabilities. Our mission creates play, dignity and social equity for children with disabilities through inclusive playgrounds and education programs that unite children of all abilities. Inclusion Matters by Shane's Inspiration has grown into a powerful network of 80 inclusive, sensory and literacy-rich playgrounds throughout the world. Our Together, We Are Able education program is in over 67 countries and transforms the playgrounds into classrooms where children with and without disabilities learn to see beyond their differences.

Mission: United people, ideas, and resources to advance the common good.Working side-by-side with the community, Mile High United Way takes on the biggest, most complex issues facing Metro Denver, Boulder, and Broomfield. Our united approach changes the odds for the children, families, and individuals in our community, and moves them out of poverty.We serve the Metro Denver and Boulder communities across seven counties: Adams, Arapahoe, Denver, Douglas, Jefferson, Boulder, and Broomfield

LIFT’s mission is to help community members achieve economic stability and well-being. They are working to establish a new standard for holistic and enduring solutions in our country’s fight against poverty.

To introduce low-cost compost toilets in order to reduce disease and provide dignity for people living without basic sanitation To reduce reliance on chemical fertilizers by producing organic compost products that can improve soil and improve food security To teach people how to compost organic wastes and protect water resources To promote EcoSan and composting as viable solutions to water-based sanitation systems

Big Cat Rescue, one of the world’s largest accredited sanctuaries for exotic cats, is a leading advocate in ending the abuse of captive big cats and saving wild cats from extinction. Care of our cats. The narrow mission of Big Cat Rescue is to provide the best permanent home we can for the abused, abandoned and retired cats in our care. We do this by building enclosures in a very natural habitat with foliage and shelter on our 67 acre site, by providing the best nutritional and medical care possible, and by having active operant conditioning and enrichment programs to provide for their physical and psychological well being. Education. The broader mission of the sanctuary is to reduce the number of cats that suffer the fate of abandonment and/or abuse and to encourage preservation of habitat and wildlife. We urge people to behave in a way that will support these goals by teaching people about the plight of the cats, both in the wild and in captivity. We accomplish this through educational guided tours, educational programs for young people, and by maintaining a website that is the world's largest and best resource for information about exotic cats.

The Multiple Sclerosis Association of America (MSAA) is a leading resource for the entire MS community, improving lives today through vital services and support.

Big Brothers Big Sisters of Greater Los Angeles (BBBSLA) is a youth empowerment organization whose mission is to create and support one-to-one mentoring relationships that ignite the power and promise of youth. Los Angeles is home to one of the most diverse populations in the country and along with being one of the largest affiliates of Big Brothers Big Sisters of America, BBBSLA is also one of the largest youth mentoring organizations in Southern California. Every year, we impact nearly 1,500 children throughout Los Angeles County—many of whom are referred to as being “at-risk” or “high-risk” youths. With the help of our amazing staff, army of selfless volunteers and generous donors, we continue to empower lives and provide our Littles with the opportunities and skill sets they need and deserve in order to achieve, succeed, and awaken their full potential.

NetHope's mission has a clear focus: to be a catalyst for collaboration among international humanitarian organizations. By working together to solve problems and share knowledge, we help ensure that our members have access to the best information and communication technology and practices when serving people in the developing world. We do this by working across our membership as a highly collaborative team, solving common technology problems, fostering strong relationships with private industry, and educating our members and the wider community of humanitarian organizations worldwide.

Be The Match Foundation supports the life-saving mission of Be The Match/National Marrow Donor Program, ensuring that patients diagnosed with blood cancers such as leukemia and other diseases get the marrow or cord blood transplant they need for a second chance at life. A transplant offers hope for a cure. We connect patients with their genetically matched donors and provide comprehensive support throughout the transplant journey, from diagnosis through recovery.